Chromatin occupancy of key transcriptional regulators in the presence of the BET bromodomain inhibitor JQ1. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA179218
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资源简介：
MM1.S cells are an aggressive dexamethasone sensitive multiple myeloma cell line whose transcritional program is driven by deregulated c-Myc activity. We present ChIP-seq analysis of key transcritional regulators that are implicated the c-Myc transcriptional network in MM1.S cells treated with vehicle or 500nM JQ1. Overall design: Brd4, Cdk9, cMyc, Max, Med1, RNA Pol II, and the chromatin modifications H3K4me3 and H3K27Ac were profiled in MM1.S cells treated with 500nM JQ1 for 24hr
创建时间：
2012-11-08
