The crystal structure of glycogen phosphorylase in complex with 11
收藏Protein Data Bank Japan2025-04-09 更新2026-03-21 收录
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The crystal structure of glycogen phosphorylase in complex with 11 Descriptor: (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1,3-thiazol-4-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... Authors: Kyriakis, E, Papaioannou, O.S.E, Solovou, T.G.A, Skamnaki, V.T, Leonidas, D.D. Deposit date: 2019-06-28 Release date: 2020-02-19 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
创建时间：
2019-06-28
