Summary statistics for "Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's Disease"
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These are the burden test results (summary statistics) for the publication: "Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s Disease", Nature Genetics, 2022. <em>Format: tab-separated-value.</em> <em>Fields:</em> <em>gene_stable_id: Ensembl gene id</em> <em>gene_name: standard gene name</em> <em>pvalue: burden test significance (likelihood ratio test, population structure correction based on 6 PCA components)</em> <em>cmac_all: sum of minor allele dosages across all contributing samples and variants</em> <em>group: variant group (LOF, LOF+REVEL>=75, LOF+REVEL>=50, LOF+REVEL>=25, see publication methods for further selection criteria).</em> <em>beta/se: beta/se of logistic ordinal regression (see publication methods). Positive = risk-increasing. Negative = risk-decreasing.</em>
