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In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.

ChEBI2015-01-30 更新2026-07-21 收录

药物肝毒性

肝细胞模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62547 数据链接链接失效反馈

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资源简介：

In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.

应用场景：

创建时间：

2015-01-30

药物肝毒性

斑马鱼毒理模型

Zebrafish larvae treated with triptolide (5 dpf larvae after exposure to triptolide (1.6μM) for 6 hours) or vehicle control. A total of 16 sequencing experiments were performed (control N=8 and treatm

NIAID Data Ecosystem60

Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6

干细胞类器官

肝细胞模型

Human induced pluripotent stem cells (hiPSCs) have potential for personalized and regenerative medicine. While most methods of utilizing these cells have focused on deriving homogenous populations of

NIAID Data Ecosystem40

Table_3_A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies.docx

药物肝毒性

体外肝模型

The poor predictability of human liver toxicity is still causing high attrition rates of drug candidates in the pharmaceutical industry at the non-clinical, clinical, and post-marketing authorization

NIAID Data Ecosystem30

Effects of Methotrexate (MTX) and Sitagliptin (Sita) on oxidative stress markers in the liver.

药物肝毒性

氧化应激标志物

Effects of Methotrexate (MTX) and Sitagliptin (Sita) on oxidative stress markers in the liver.

NIAID Data Ecosystem60

Gene expression data from primary human hepatocytes treated with GGF2 for 6, 24, or 72 h or 24 h with a 48 h washout.

药物肝毒性

基因表达谱分析

GGF2 is a recombinant human neuregulin-1β in development for chronic heart failure. Phase 1 clinical trials of GGF2 were put on hold when transient elevations in serum aminotransferases and total bili

NIAID Data Ecosystem40

In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.

资源简介：

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