Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor KM-05-080
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Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor KM-05-080 Descriptor: 8-(1~{H}-benzimidazol-2-ylmethyl)-3-cyclopropyl-7-(phenylmethyl)purine-2,6-dione, FE (III) ION, Tryptophan 5-hydroxylase 1 Authors: Schuetz, A, Mallow, K, Nazare, M, Specker, E, Heinemann, U. Deposit date: 2022-04-08 Release date: 2022-09-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.94678366 Å) Cite: Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem., 65, 2022
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2022-04-08
