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Crystal Structure of PAK4 in complex with inhibitor 55

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal Structure of PAK4 in complex with inhibitor 55 Descriptor: Serine/threonine-protein kinase PAK 4, [1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]-[(3S)-3-methylpiperazin-1-yl]methanone Authors: Zhao, F, Li, H. Deposit date: 2020-08-06 Release date: 2021-08-11 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of 6-ethynyl-1H-indole-3-carboxamide Derivatives as Highly Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors to be published

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2020-08-06
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