Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure

Protein Data Bank Japan2024-03-06 更新2026-03-21 收录

心力衰竭药物设计

ASK1抑制剂优化

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Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure Descriptor: 2-(6-{4-[(2R)-1-hydroxypropan-2-yl]-4H-1,2,4-triazol-3-yl}pyridin-2-yl)-6-[(propan-2-yl)oxy]-2,3-dihydro-1H-isoindol-1-one, Mitogen-activated protein kinase kinase kinase 5 Authors: Dougan, D.R. Deposit date: 2017-02-01 Release date: 2017-06-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure. ACS Med Chem Lett, 8, 2017

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2017-02-01

Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure

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