RIP4 inhibits STAT3 Signaling to sustain Lung Adencarcinoma Differentiation. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA320749
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资源简介:
Evaluation of the role of RIP4 in lung adenocarcinoma revealed that RIP4 inhibits STAT3 signaling in vitro and in vivo. Repression of RIP4 enhanced STAT3 signaling activation in KRAS LSL/G12D/wt; p53flox/flox murine tumors. This promoted cancer dedifferentiation through ECM remodeling Overall design: Investigation of transcriptional changes in KP tumors expressing shRNA against RIP4 or p53 (control) by microarray (Mouse gene 2.0 ST array from affymetrix)
创建时间:
2016-05-05



