Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (71% substrate/29% product at 24 hours)

Protein Data Bank Japan2023-09-27 更新2026-03-21 收录

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https://pdbj.org/mine/summary/5cl4

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Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (71% substrate/29% product at 24 hours) Descriptor: 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ... Authors: Mullins, E.A, Eichman, B.F. Deposit date: 2015-07-16 Release date: 2015-10-28 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.866 Å) Cite: The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527, 2015

创建时间：

2015-07-16