Classification of lead defensin mimetics.
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N.D: Not Determinable by SPR. Bacterial killing: Concentration resulting in 100% killing after exposure of compound to bacteria for 30 min, determined by modified vCC assays [26]. Binding to immobilized 3-Lipid II was analyzed by Surface Plasmon Resonance. C50% equals compound concentration resulting in 50% cell survival measured by MTT assay following incubation for 24 h (Caco-2) or 4 h (Jurkat).
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2015-12-02
