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Additional file 1 of Genetic-by-age interaction analyses on complex traits in UK Biobank and their potential to identify effects on longitudinal trait change

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Additional file 1: Table S1. Study descriptives. Table S2. Controlled power. Table S3. Descriptive summary of GWAS. Table S4. Gene-age interaction loci. Table S5. Gene prioritization by DEPICT and FUMA at 44 genetic-by-age interaction loci. Table S6. Marginal effect region lead variants. Table S7. Sensitivity analyses for cohort and selection/survival effects. Table S8. Pulse wave arterial stiffness index in UKB. Table S9. Sensitivity analysis adjusting for GxBMI. Table S10. Tissue enrichment analyses by FUMA for genetic-by-age interaction loci for pulse pressure. Table S11. Tissue enrichment analyses by DEPICT for genetic-by-age interaction loci for pulse pressure. Table S12. FORGE2 variant-to-tissue mapping.

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2024-11-29
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