carbovir + IMP => carbovir monophosphate + inosine
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NT5C2 catalyzes the reaction of carbovir and IMP to form carbovir monophosphate and inosine (Johnson and Fridland 1989; Miller et al. 1992). The enzyme was originally identified as a high-Km soluble 5'-nucleotidase most active on IMP and GMP (Spychala et al. 1988). Its active form is a tetramer (Wallden et al. 2007).
NT5C2催化羧基病毒和IMP的反应,形成羧基病毒单磷酸盐和肌苷(Johnson 和 Fridland,1989;Miller 等人,1992)。该酶最初被鉴定为一种高Km溶解性5'-核苷酸酶,对IMP和GMP的活性最高(Spychala 等人,1988)。其活性形式为四聚体(Wallden 等人,2007)。
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