Analysis of MHC class II peptides

NIAID Data Ecosystem2026-05-10 收录

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Peptides eluted from MHC class II (I-Ak) to which HEL protein was pulsed.

创建时间：

2026-03-09

Machine learning optimization of peptides for presentation by class II MHCs

We present a machine learning method to optimize the presentation of peptides by class II MHCs and test peptides using a high a throughput yeast-display assay.

NIAID Data Ecosystem10

Peptide – human class II MHC docking results.

Self-docking results are indicated by asterisks. The PDB ID for the MHC structure used in docking is shown in parentheses for each allotype. All-atom RMSDs were calculated for all non-hydrogen atoms i

Figshare2015-12-02 更新00

Peptide – murine class II MHC docking results.

See the Table 1 caption for details. The correct peptide sequence for PDB entry 2IAD was unknown since it differs between the reference and the PDB file so docking of this peptide was not performed.

Figshare2015-12-02 更新00

Catalysis of peptide dissociation from class II MHC-peptide complexes

Certain peptides such as dynorphin A [dynA-(1–13)] enhance the release of antigenic peptides bound to class II MHC molecules at neutral pH. This enhanced release has been termed push off. Previous wor

PubMed Central1999-06-08 更新20

Machine learning optimization of peptides for presentation by class II MHCs

We present a machine learning method to optimize the presentation of peptides by class II MHCs and test peptides using a high a throughput yeast-display assay.

NIAID Data Ecosystem40