Enantioselective Decarboxylative Arylation of α‑Amino Acids via the Merger of Photoredox and Nickel Catalysis
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https://figshare.com/articles/dataset/Enantioselective_Decarboxylative_Arylation_of_Amino_Acids_via_the_Merger_of_Photoredox_and_Nickel_Catalysis/2074171
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资源简介:
An asymmetric decarboxylative
Csp3–Csp2 cross-coupling
has been achieved via the synergistic
merger of photoredox and nickel catalysis. This mild, operationally
simple protocol transforms a wide variety of naturally abundant α-amino
acids and readily available aryl halides into valuable chiral benzylic
amines in high enantiomeric excess, thereby producing motifs found
in pharmacologically active agents.
创建时间:
2016-02-10



