BackgroundStudies of the genetic basis of drug response could help clarify mechanisms of drug action/metabolism, and facilitate development of genotype-based predictive tests of efficacy or toxicity (
Additional file 1: Table S1. Established genetic variants in the HMGCR, PCSK9 and NCP1L1 gene that mimic statins, PCSK9 inhibitors and ezetimibe respectively]. Table S2. Correlation matrix for genetic
Objectives We evaluated the cost and efficiency of routine HLA-B*15∶02 screening to prevent carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-SJS/TEN) in Hong Kong. Me
Background: The successful integration of pharmacogenetic (PGx) testing into clinical care will require attention to patient attitudes. In this study, we aimed to identify the major reasons why
