Inhibition of AK4 expression increases drug sensitivity and elevates mitochondrial ATP synthesis

ChEBI2016-03-31 更新2026-07-12 收录

药物敏感性机制

线粒体能量代谢

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Inhibition of AK4 expression increases drug sensitivity and elevates mitochondrial ATP synthesis

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2016-03-31

Mitochondrial DNA depletion by ethidium bromide decreases neuronal mitochondrial creatine kinase: Implications for striatal energy metabolism

线粒体能量代谢

帕金森病运动障碍

Mitochondrial DNA (mtDNA), the discrete genome which encodes subunits of the mitochondrial respiratory chain, is present at highly variable copy numbers across cell types. Though severe mtDNA depletio

NIAID Data Ecosystem80

Additional file 4: Table S3. of Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3

癌症信号通路

药物敏感性机制

Results of gene set enrichment analysis (GSEA) of the obtained three gene expression profiles of differences between sensitive and insensitive lung cancer cell lines. For that we used geneXplain platf

Figshare2018-02-14 更新60

Crystal structure of bovine coupling Factor B bound with phenylarsine oxide

蛋白质晶体学

线粒体能量代谢

Crystal structure of bovine coupling Factor B bound with phenylarsine oxide Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP synthase subunit s, mitochondrial, ... Authors: Stroud, R.M, Lee,

Protein Data Bank Japan2023-08-30 更新30

Raw data of "Structural Basis of Complex Formation Between Mitochondrial Anion Channel VDAC1 and Hexokinase-II"

蛋白质相互作用结构分析

线粒体能量代谢

Raw data set for the manuscript entitled "Structural Basis of Complex Formation Between Mitochondrial Anion Channel VDAC1 and Hexokinase-II"

Figshare2021-04-29 更新80

Effect of different drugs on the rates of ATP synthesis and heat production.

线粒体能量代谢

药物药效评估

Experiments were performed with coupled mitochondria with faf-BSA and GDP and in the absence of Ca2+. Essentially the same results were obtained in presence of Ca2+.

NIAID Data Ecosystem50

Inhibition of AK4 expression increases drug sensitivity and elevates mitochondrial ATP synthesis

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