Clinical trials of hypothermia after pediatric cardiac arrest have not seen robust improvement in functional outcome, possibly because of the long delay in achieving target temperature. Previous work
Hypothermia is increasingly used as a therapeutic measure against brain injury. However, the cellular mechanisms underpinning its actions are complex and not fully elucidated. Astrocytes are the most
The number and percentage of included studies with each study characteristic is presented. Means are presented with standard deviations, and medians with interquartile ranges (IQR).
Therapeutic hypothermia is the standard of clinical care for moderate neonatal hypoxic-ischemic encephalopathy. We investigated the independent and interactive effects of hypoxia-ischemia (HI) and tem
