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Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2zm3
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Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor Descriptor: (4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione, Insulin-like growth factor 1 receptor Authors: Xu, W, Mayer, S.C, Boschelli, F, Johnson, M, Dwyer, B. Deposit date: 2008-04-10 Release date: 2008-06-10 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment Bioorg.Med.Chem.Lett., 18, 2008
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2008-04-10
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