Zinc finger and BTB domain containing 16 functions as a downstream of Osterix during the osteoblastic differentiation of human multipotent mesenchymal stromal cells. Homo sapiens

Multipotent mesenchymal stem cells (MSCs) have the ability to differentiate into osteoblasts. The expression of ZBTB16 increased during osteoblastic differentiation. Knockdown of ZBTB16 impaired osteoblastic differentiation. ZBTB16 regulates osteoblastic differentiation in MSCs as the downstream of Osterix.