Functional neuroimaging studies in chronic cannabis users.

Note: Yr. = years; CU = Cannabis users; HC = Healthy controls; M = Male; F = Female; SD = Standard deviation; FL = Frontal lobe; PL = Parietal lobe; TL = Temporal lobe; OL = Occipital lobe; I = Insula; BG = Basal ganglia; Cb = Cerebellum; fMRI = Functional magnetic resonance imaging; SPECT = Single photon emission tomography; PET = Positron emission tomopgraphy; DSC = Dynamic susceptibility contrast; VT = Distribution volume; BPND = Non-displaceable binding potential; FDG = Fludeoxyglucose; L = Left hemisphere; R = Right hemisphere; ROI = Region of interest; MSIT = Multi-Source Interference Task; CBF = Global cerebral blood flow; rCBF = Regional cerebral blood flow; BOLD = blood oxygenation-level dependent; NE = Not specified; PFC = Prefrontal cortex; DLPFC = Dorsolateral prefrontal cortex; VMPFC = Ventromedial prefrontal cortex; OFC = Orbitofrontal cortex; ACC = Anterior cingulated cortex; NAcc = Nucleus accumbens; VS = Ventral striatum; STG = Superior temporal gyrus; SWM = Spatial working task; IGT = Iowa Gambling Task.*If not otherwise specified, results are presented in terms of chronic cannabis users.○ = Significant differences; ○ = Non-significant differences; = Not examined.**Two subjects in the marijuana group met criteria for alcohol abuse.***Four teens in the chronic cannabis group met criteria for alcohol use disorder, two cases of abuse and two cases of dependence.†One control, three recent users and two abstinent users met criteria for alcohol use disorders.†Multiple comparison correction.