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Role of Arid3a in proliferation and differentiation of intestinal epithelial cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP395275
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To investigate the role of Arid3a in the intestinal epithelium, we generated an inducible conditional knockout model (VillinCreERT2;Arid3afl/fl -Arid3a cKO) and we compared the gene expression analysis to WT animals (ViliinCreERT2). Animals were injected intraperitoneally with tamoxifen to induce gene deletion. Overall design: Differences in chromatin accessibility between WT and Arid3a cKO animals and footprinting analysis at 1 month after tamoxifen administration.
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2024-10-09
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