SNPs associated with facial shape features from discovery GWAS and their replications.

SNPs with P<5e-8 in discovery phase are shown, one SNP per loci; symmetric facial features are shown for both when one is involved. FreqEff, the overall frequency of the effect allele in all cohorts. Units in the discovery and SYS cohorts are in millimeters. % in SYS, the percentage of P values<0.05 for testing 1,540 pair-wise distances between 56 landmarks. % in BLTS+TwinsUK, the percentage of P values<0.05 for testing 28 pair-wise distances between 8 landmarks. *Zygions could not be reliably derived from BLTS and TwinsUK 2D portrait photos.