Human HFF cells large rearrangements detection after CRISPR-Cas9 nuclease (Supplentary Fig. 4)

ABRAXAS2 gene editing by CRISPR-Cas9 nuclease or before editing in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS or without cell sorting and large rearrangements confirmation in chromosome 10q. Three-condition experiment,edited or no edited HFF vs Illumina reference CGH-Array. Fluorescent positive cell bulk or bulk without cell sorting after ABRAXAS2 gene editing or before editing.