Cannabinoid exposure and altered DNA methylation in rat and human sperm
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https://tandf.figshare.com/articles/Cannabinoid_exposure_and_altered_DNA_methylation_in_rat_and_human_sperm/7430639
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资源简介:
Little is known about the reproductive effects of paternal cannabis exposure. We evaluated associations between cannabis or tetrahydrocannabinol (THC) exposure and altered DNA methylation in sperm from humans and rats, respectively. DNA methylation, measured by reduced representation bisulfite sequencing, differed in the sperm of human users from non-users by at least 10% at 3,979 CpG sites. Pathway analyses indicated Hippo Signaling and Pathways in Cancer as enriched with altered genes (Bonferroni p
提供机构:
Taylor & Francis
创建时间:
2018-12-06



