meta_data

<b>tblhctmeta.csv: Day and source of hematopoietic cell transplant (HCT) for 1,279 patients</b>PatientID: deidentified identifier of patientsDayOfTransplant: deidentified day of HCTHCTSource: hematopoietic cell sources for HCT patients (BM_unmodified: bone marrow; PBSC_unmodified: peripheral blood stem cells; TCD: T-cell depleted; cord: cord blood)Disease: disease of patientswbcPatientId, autoFmtPatientId, nejmPatientId: identifiers for the same patients if they were also included in another previous study (wbcPatientId: Schluter, J. et al. 2019. The gut microbiota influences circulatory immune cell dynamics in humans. <i>BioRxiv</i>; autoFmtPatientId: Taur, Y. et al. 2018. Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant. <i>Science Translational Medicine</i> 10(460); nejmPatientId: Peled, J.U. et al. 2020. Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation. <i>New England Journal of Medicine</i>, <i>382</i>(9), pp.822-834.)EngraftmentDayRelativeToNearestTransplantDay: engraftment day relative to the nearest day of bone marrow transplant<br><br><b>tbldrug.csv: Timing and route of drug administration for 1,279 patients</b>PatientID: deidentified identifier of patientsStartTimepoint: deidentified day when drug administration startedStopTimepoint: deidentified day when drug administration stopped (including the day)Factor: name of the drugCategory: category of the drugAntiInfective: whether the drug is an anti-infective agentRoute: route of drug administrationStartDayRelativeToNearestTransplantDay/StopDayRelativeToNearestTransplantDay: start/stop day of the drug administration relative to the nearest day of bone marrow transplant<br><b>tblInfectionsCidPapers.csv: Day of positive blood cultures for 457 patients </b>(include only microbes analyzed in<b> </b>1. Taur, Y., et al. 2012. Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. <i>Clinical infectious diseases</i>, <i>55</i>(7), pp.905-914; 2. Stoma, I., et al. 2020. Compositional flux within the intestinal microbiota and risk for bloodstream infection with gram-negative bacteria. <i>Clinical Infectious Diseases</i>.)PatientID: deidentified identifier of patientsTimepoint: deidentified day of infectionInfectiousAgent: the bacteria causing infectionsDayRelativeToNearestTransplantDay: day of infection relative to the nearest day of bone marrow transplant<br><b>tblbc.csv: Daily measurements of white blood cells, platelets and red blood cells for 1,279 patients</b>PatientID: deidentified ID of patientsTimepoint: deidentified day of blood cell measurementBloodCellType: immature monocyte cells (ImmatureMonocytes), sezary cells (SezaryCells), variant lymphocyte cells (VariantLymphocytes), immature granulocyte cells (ImmatureGranulocytes), band cells (BandCells), basophil cells (Basophills), blast cells (BlastCells), eosinophil cells (Eosinophils), lymphocyte cells (Lymphocytes), neutrophil cells (Neutrophils), monocyte cells (Monocytes), platelet (Platelets), total white blood cells (WBCtotal), total red blood cells (RBCtotal)Value: blood cell counts<br>Unit: K per uL (1,000 cells/uL) or M per uL (1,000,000 cells/uL)DayRelativeToNearestTransplantDay: day of blood cell measurement relative to the nearest day of bone marrow transplant<br><br><b>tbltemperature.csv: </b>temperatures for 1,317 patientsPatientID: deidentified identifier of patientsTimepoint: deidentified day when patient temperature was measuredMaxTemperature: Maximum temperature (unit: Fahrenheit) recorded on that day for that patientDayRelativeToNearestTransplantDay: day of temperature measurement relative to the nearest day of bone marrow transplant<br><br><b>tblVanA.csv</b>: Results of PCR detection for <i>vanA </i>gene for 7,589 samplesSampleID: stool sample identifier VanA: whether <i>vanA</i> gene is detected in the sample<b>tblhctmeta.csv：1279例患者造血干细胞移植（hematopoietic cell transplant, HCT）的日期与供源</b> PatientID：患者去标识化标识符 DayOfTransplant：造血干细胞移植的去标识化日期 HCTSource：造血干细胞移植供源（BM_unmodified：未修饰骨髓；PBSC_unmodified：未修饰外周血干细胞；TCD：T细胞耗竭型；cord：脐带血） Disease：患者基础疾病 wbcPatientId、autoFmtPatientId、nejmPatientId：若患者同时纳入既往另一项研究，则为对应患者的标识符（wbcPatientId：Schluter J. 等, 2019. 肠道菌群影响人类循环免疫细胞动态. <i>BioRxiv</i>；autoFmtPatientId：Taur Y. 等, 2018. 自体粪便菌群移植重建抗生素治疗患者肠道菌群. <i>Science Translational Medicine</i> 10(460)；nejmPatientId：Peled J.U. 等, 2020. 菌群作为异基因造血干细胞移植死亡率预测因子. <i>New England Journal of Medicine</i>, 382(9): 822-834.） EngraftmentDayRelativeToNearestTransplantDay：相对于最近一次骨髓移植日期的造血植入天数 <br><br><b>tbldrug.csv：1279例患者药物给药的时机与途径</b> PatientID：患者去标识化标识符 StartTimepoint：药物给药开始的去标识化日期 StopTimepoint：药物给药停止的去标识化日期（含停药当日） Factor：药物名称 Category：药物类别 AntiInfective：该药物是否为抗感染剂 Route：药物给药途径 StartDayRelativeToNearestTransplantDay/StopDayRelativeToNearestTransplantDay：相对于最近一次骨髓移植日期的药物给药开始/停止天数 <br><b>tblInfectionsCidPapers.csv：457例患者血培养阳性日期</b>（仅纳入以下2项研究中分析的微生物：1. Taur Y. 等, 2012. 肠道定植与异基因造血干细胞移植患者菌血症风险. <i>Clinical infectious diseases</i>, 55(7): 905-914；2. Stoma I. 等, 2020. 肠道菌群组成动态与革兰阴性菌血流感染风险. <i>Clinical Infectious Diseases</i>.） PatientID：患者去标识化标识符 Timepoint：感染发生的去标识化日期 InfectiousAgent：感染致病菌 DayRelativeToNearestTransplantDay：相对于最近一次骨髓移植日期的感染发生天数 <br><b>tblbc.csv：1279例患者白细胞、血小板与红细胞的每日检测值</b> PatientID：患者去标识化标识符 Timepoint：血细胞检测的去标识化日期 BloodCellType：血细胞类型（未成熟单核细胞（ImmatureMonocytes）、塞扎里细胞（SezaryCells）、变异淋巴细胞（VariantLymphocytes）、未成熟粒细胞（ImmatureGranulocytes）、杆状核粒细胞（BandCells）、嗜碱性粒细胞（Basophills）、原始细胞（BlastCells）、嗜酸性粒细胞（Eosinophils）、淋巴细胞（Lymphocytes）、中性粒细胞（Neutrophils）、单核细胞（Monocytes）、血小板（Platelets）、白细胞总数（WBCtotal）、红细胞总数（RBCtotal）） Value：血细胞计数 Unit：每微升千个细胞（K per uL，即1000个细胞/μL）或每微升百万个细胞（M per uL，即1000000个细胞/μL） DayRelativeToNearestTransplantDay：相对于最近一次骨髓移植日期的血细胞检测天数 <br><br><b>tbltemperature.csv：1317例患者体温数据</b> PatientID：患者去标识化标识符 Timepoint：患者体温测量的去标识化日期 MaxTemperature：当日记录的患者最高体温（单位：华氏度） DayRelativeToNearestTransplantDay：相对于最近一次骨髓移植日期的体温测量天数 <br><br><b>tblVanA.csv：7589份样本的vanA基因聚合酶链式反应（polymerase chain reaction, PCR）检测结果</b> SampleID：粪便样本标识符 VanA：样本中是否检出vanA基因