Bcl11a is essential for B-1a cell maintenance during aging

NIAID Data Ecosystem2026-05-10 收录

免疫衰老

细胞功能调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE272988 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-09-18

Age-associated loss of lamin-B leads to systemic inflammation and gut hyperplasia

免疫衰老

肠道增生病理

Aging of immune organs, termed as immunosenescence, is suspected to promote systemic inflammation and age-associated disease. The cause of immunosenescence and how it promotes disease, however, has

NIAID Data Ecosystem40

Effect of Rosa roxburghii fruit extracts to gene expression of mesenchymal stem cells

天然产物抗衰老机制

细胞功能调控

Here we found Rosa roxburghii fruit extracts effectively increase TERT expression and telomerase activity in cultured human mesenchymal stem cells. Both Rosa roxburghii fruit extracts by freeze drying

NIAID Data Ecosystem20

Table 1_TGF-β-driven NK Cells plasticity in hepatocellular carcinoma.docx

肿瘤免疫微环境

细胞功能调控

BackgroundHepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, with limited curative options for advanced disease. Natural Killer (NK) cells are critical innate immune effect

NIAID Data Ecosystem00

Effect of chronic epinephrine exposure on gene expression in MIN6 cells

细胞功能调控

激素转录组学

Chronic exposure to epinephrine enhances the compensatory insulin secretion in MIN6 cells while persistently inhibiting cell proliferation. The molecular mechanisms underlying these phenomena were inv

NIAID Data Ecosystem30

DataSheet_1_Co-Expression of TIGIT and Helios Marks Immunosenescent CD8+ T Cells During Aging.docx

免疫衰老

CD8+T细胞标志物

Aging leads to alterations in the immune system that result in ineffective responsiveness against pathogens. Features of this process, collectively known as immunosenescence, accumulate in CD8+ T cell

NIAID Data Ecosystem20

Bcl11a is essential for B-1a cell maintenance during aging

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