Discovery of small molecules binding to KRAS via high affinity antibody fragment competition method.
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Discovery of small molecules binding to KRAS via high affinity antibody fragment competition method. Descriptor: CITRIC ACID, DI(HYDROXYETHYL)ETHER, GTPase KRas, ... Authors: Cruz-Migoni, A, Ehebauer, M.T, Phillips, S.E.V, Quevedo, C.E, Rabbitts, T.H. Deposit date: 2017-07-03 Release date: 2018-08-22 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment. Nat Commun, 9, 2018
创建时间:
2017-07-03



