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Toxoplasma gondii transcription factor AP2XII-8: a key regulator of G1 phase progression and parasite division

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Figshare2025-07-05 更新2026-04-28 收录
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https://figshare.com/articles/dataset/_b_i_Toxoplasma_gondii_i_b_b_transcription_factor_AP2XII-8_a_key_regulator_of_G1_phase_progression_and_parasite_division_b_/29483267
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The uploaded files are the original data tables that directly support the statistical data and analyses presented in our related research paper. Our study delved deep into the functional characteristics of the C/G1 phase - expressed ApiAP2 transcription factor TgAP2XII - 8 in Toxoplasma gondii tachyzoites.These datasets include quantitative data used to evaluate the growth defects observed after the conditional knockdown of TgAP2XII - 8. The data also document the asexual division disorders we identified during the research. Moreover, they contain measurements related to the disruption of the parasite's cell cycle progression, particularly the accumulation in the G1 phase following the depletion of TgAP2XII - 8.In addition, these tables contain the results of our RNA - seq and CUT&Tag analyses, which led to our discovery of the role of TgAP2XII - 8 as an activator of ribosomal proteins expressed in the G1 phase. In summary, these are the very original data tables we are uploading. They provide crucial quantitative evidence that supports the conclusions we drew in our study regarding the key role of TgAP2XII - 8 in regulating the cell cycle of Toxoplasma gondii tachyzoites.
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2025-07-05
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