SAMHD1 HD domain bound to decitabine triphosphate
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6cm2
下载链接
链接失效反馈官方服务：
资源简介：
SAMHD1 HD domain bound to decitabine triphosphate Descriptor: 6-amino-3-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-3,4-dihydro-1,3,5-triazin-2(1H)-one, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Oellerich, T, Schneider, C, Thomas, D, Knecht, K.M, Buzovetsky, O, Kaderali, L, Schliemann, C, Bohnenberger, H, Angenendt, L, Hartmann, W, Wardelmann, E, Rothenburger, T, Mohr, S, Scheich, S, Comoglio, F, Wilke, A, Strobel, P, Serve, H, Michaelis, M, Ferreiros, N, Geisslinger, G, Xiong, Y, Keppler, O.T, Cinatl, J. Deposit date: 2018-03-02 Release date: 2019-06-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML. Nat Commun, 10, 2019
创建时间：
2018-03-02
