Effect of salivary exosomal miR-25-3p on periodontitis with insulin resistance

Salivary exsomal miRNAs may play important role in the pathogenesis of chronic inflammatory disease, such as periodontitis. There are many studies which suggested the connection between periodontitis and systemic disease, however, the role of specific miRNA as a intersection of periontitis and diabetes are not elucidated. We suggested miR-25-3p as possible common mediator in the pathogenesis of periodontitis and diabetes. Overall design: Salivary exosomal miRNA profiles of Control and Type2 Diabetes patients