E_max and pD₂ values of Ach-induced relaxation in mesenteric arteries (MA-PVAT) and in the perfused mesenteric bed (MB).

MA (Isolated mesenteric arteries), MB (perfused mesenteric bed). Emax, is the maximal relaxation to acetylcholine in % of precontraction to noradrenaline. pD2, is the negative logarithm of molar concentration of Ach causing half maximal responses. AUC, is the area under concentration-response curves expressed in mmHg for MB and mg for MA. Data are expressed as mean ± S.E.M., n≥5. **p<0.01, ***p<0.001, compared to their corresponding matched control groups. #p<0.05, ###p<0.001 compared to the control group.