Functional distributions of regulated genes in some clusters by Database for Annotation Visualization and Integrated Discovery (DAVID) analysis.

Functional analysis of regulated genes was performed using Functional Annotation Tool (DAVID Bioinformatics Resources) according to GO term (biological process, molecular function and cellular component) on several clusters: cluster 8 which was down in all models, cluster 15 which was up in all models, clusters 2 and 7 which were down in polyQ models only, cluster 14 which was up in polyQ models only, cluster 4 which was up only in HSA-AR and clusters 10 and 11 which were up only in HSA-AR.