Short-term feasibility studies of the 8 lead compounds in reducing Aβ neuropathology in Tg2576 mouse model of AD.
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https://figshare.com/articles/dataset/_Short_term_feasibility_studies_of_the_8_lead_compounds_in_reducing_A_946_neuropathology_in_Tg2576_mouse_model_of_AD_/975943
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Tg2576 mice were treated with 2 mg/kg/day of the candidate compound delivered through their drinking water for 4 weeks, Body weight, brain neuropathology including oligomeric Aβ as well as total brain Aβ were compared to vehicle-treated control Tg2576 mice (n = 5 per group, *p
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2015-12-02
