Capital letters show sequences that are cognate between a target oligonucleotide and the probe, with the restriction site shown in bold. 1The total length of a target sequence that is complementary to

NIAID Data Ecosystem50

Kinetics of duplex formation for individual DNA strands within a single protein nanopore

分子生物学

核酸杂交

A single oligonucleotide was covalently attached to a genetically engineered subunit of the heptameric protein pore, α-hemolysin, to allow DNA duplex formation inside the pore lumen. Single-channel cu

PubMed Central2001-10-23 更新20

The Smc5/6 complex counteracts R-loop formation at highly transcribed genes in cooperation with RNase H2

转录调控

核酸杂交

The R-loop is a common transcriptional by-product that consists of an RNA-DNA duplex joined to a displaced strand of genomic DNA. While the effects of R-loops on health and disease are well establishe

DataONE2025-02-19 更新60

HIV-1 POLYPURINE HYBRID, R(GAGGACUG):D(CAGTCCTC), NMR, 18 STRUCTURES

HIV-1逆转录

核酸杂交

HIV-1 POLYPURINE HYBRID, R(GAGGACUG):D(CAGTCCTC), NMR, 18 STRUCTURES Descriptor: DNA (5'-D(*CP*AP*GP*TP*CP*CP*TP*C)-3'), RNA (5'-R(*GP*AP*GP*GP*AP*CP*UP*G)-3') Authors: Fedoroff, O.Y, Ge, Y, Reid, B.R

Protein Data Bank Japan2024-05-22 更新20

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