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Comparison of Corynebacterium glutamicum wild type with C. glutamicum ChrS-Ala245fs

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE206796
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In an evolutionary experiment on high hemin concentrations, a frameshift mutation in the ChrS gene was figured out to be striking in survival at high hemin concentrations (Ala245fs). Apart from high upregulation of heme exporter hrtB, microarrays should reveal further different controlled genes compared to the WT. The aim was to identify genes differentially expressed genes between the C. glutamicum ChrS-Ala245fs mutant and WT reference strain. Triplicate experiments inlcuding a color swap were carried out.
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2022-10-04
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