Individual codons are listed with calculated CSC scores for mRNA half-lives determined using the SLAM-Seq protocol. mESCs were cultured under control conditions or were treated with 0.1 μg/mL G418 or
Log IC50 values for inhibition of nicotinic responses in CN21 and SH-SY5Y cells by the test compounds. Data show mean ± SEM. All values were obtained by best-fit of the Hill-equation as described in t
HEK293T ishXrn1 cells were treated with doxycycline for 3-4 days to induce knock down of Xrn1, then transfected with a luciferase reporter with a 15 bp inserted sequence from the STOML2 gene, wild-typ