Crystal Structure of KSR2:MEK1 in complex with ANP-PNP, and allosteric MEK inhibitor Selumetinib
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Crystal Structure of KSR2:MEK1 in complex with ANP-PNP, and allosteric MEK inhibitor Selumetinib Descriptor: 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2, ... Authors: Khan, Z.M, Dar, A.C. Deposit date: 2020-08-20 Release date: 2020-09-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Structural basis for the action of the drug trametinib at KSR-bound MEK. Nature, 588, 2020
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2020-08-20
