Additional file 2 of Cas9/guide RNA-based gene-drive dynamics following introduction and introgression into diverse anopheline mosquito genetic backgrounds
Here we report the development and testing of a novel self-limiting gene drive system, Killer–Rescue (K–R), in Drosophila melanogaster. This system is composed of an autoregulated Gal4 Killer (K) and
Here we report the development and testing of a novel self-limiting gene drive system, Killer–Rescue (K–R), in Drosophila melanogaster . This system is composed of an autoregulated Gal4 Killer (
Current engineered gene drive strategies rely on sexual reproduction and it was therefore thought that gene drives could not be engineered in asexual organisms such as bacteria and viruses. Here howev
Our data identifies a role for orco in Aedes aegypti mosquito reproduction. This non-olfactory role for orco results in reduction in fertility after the second gonotrophic cycle. We present the source