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Structure-activity relationship guides enantiomeric preference among potent inhibitors of B. anthracis dihydrofolate reductase

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Structure-activity relationship guides enantiomeric preference among potent inhibitors of B. anthracis dihydrofolate reductase Descriptor: (2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(3,3,3-trifluoropropyl)phthalazin-2(1H)-yl ]prop-2-en-1-one, CALCIUM ION, CHLORIDE ION, ... Authors: Bourne, C.R, Barrow, W.W. Deposit date: 2012-04-10 Release date: 2013-02-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-activity relationship for enantiomers of potent inhibitors of B. anthracis dihydrofolate reductase. Biochim.Biophys.Acta, 1834, 2013
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2012-04-10
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