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Immune-instructive polymers

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DataCite Commons2024-11-29 更新2025-04-17 收录
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https://rdmc.nottingham.ac.uk/handle/internal/8306
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资源简介:
We identify polymers which instruct different immunological responses by modulating macrophage attachment and polarisation to pro-inflammatory (M1-like) or anti-inflammatory (M2-like) phenotypes. These immune-instructive polymers were discovered using in-vitro high throughput polymer microarray screening of diverse (meth)acrylate and (meth)acrylamide libraries. The bio-instructive polymer function is validated in-vivo and analysis of the protein layer adsorbed to polymers, cytokine release and phagocytosis explored.
提供机构:
The University of Nottingham
创建时间:
2020-05-01
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