Immunogenicity of Recombinant Rabies Virus-Vectored Multivalent Vaccines Expressing FCV VP1 and FHV-1 gB/gD Genes

Name: Immunogenicity of Recombinant Rabies Virus-Vectored Multivalent Vaccines Expressing FCV VP1 and FHV-1 gB/gD Genes
Creator: Yinyi Liang; Nuan Chen; Xiaolong Li; Louisiana State University; Hongling He; Jiahao Wang; Lerong Xin; Yueze Wang; South China Agricultural University; Xiaofeng Guo; Songze Zhao; Wanxing Xie
Published: 2025-12-16T00:00:00+08:00

科学数据银行2025-12-16 更新2026-04-23 收录

兽用疫苗研发

猫科病毒免疫

数据链接：

https://www.scidb.cn/detail?dataSetId=c55e60e3088f4770b9a38b3e75b24f9a 数据链接链接失效反馈

官方服务：

资源简介：

To develop a safe and effective multivalent vaccine against feline calicivirus (FCV) and feline herpesvirus 1 (FHV-1), two recombinant rabies virus (RABV) vaccines expressing the FCV VP1 and FHV-1 gB/gD genes were constructed. The exogenous genes showed stable inheritance, and the recombinant viruses exhibited growth kinetics similar to the parental strain. After verifying the viral pathogenicity, the recombinant virus vaccines elicited neutralizing antibody responses against FCV, FHV-1, and RABV, and conferred effective protection.

提供机构：

Yinyi Liang; Nuan Chen; Xiaolong Li; Louisiana State University; Hongling He; Jiahao Wang; Lerong Xin; Yueze Wang; South China Agricultural University; Xiaofeng Guo; Songze Zhao; Wanxing Xie

创建时间：

2025-12-16