Phosphine-Catalyzed [3 + 3]-Domino Cycloaddition of Ynones and Azomethine Imines To Construct Functionalized Hydropyridazine Derivatives
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The first phosphine-catalyzed [3 + 3]-domino annulation reaction of ynones and azomethine imines has been developed. With this simple and efficient method, the functionalized hydropyridazine derivatives were obtained in good to excellent yields with highly stereoselectivies.
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2016-05-27
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