Structure of the Human G-quadruplex reveals a novel topology Descriptor: 5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION, SODIUM ION Authors: Parkinson, G.N, Lee, M.P.H, Neidle, S.
Hybrid-1R G-quadruplex with a +(lpp) loop progression Descriptor: DNA (27-MER) Authors: Jana, J, Vianney, Y.M, Weisz, K. Deposit date: 2023-11-13 Release date: 2023-12-27 Last modified: 2024-01-31 Met
Nucleic acids can fold into G-quadruplex (G4) structures that can fine tune biological processes. Proteins are required to recognize G4 structures and coordinate their function. We identify Zuo1 as a
structure of RET G-quadruplex in complex with berberine Descriptor: BERBERINE, DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3') Authors: Wang, F, Wang, C, Liu, Y, Lan, W.X, L
G-quadruplexes are higher-order DNA structures formed from guanine-rich sequences, and have been identified as attractive anticancer drug targets. Elucidating the three-dimensional structure of G-quad