ADAR1-mediated A-to-I RNA editing is essential for erythropoiesis [RNA-seq]

ChEBI2016-07-24 更新2026-07-12 收录

RNA编辑机制

红细胞生成调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-71042 数据链接链接失效反馈

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资源简介：

ADAR1-mediated A-to-I RNA editing is essential for erythropoiesis [RNA-seq]

创建时间：

2016-07-24

APOBEC3A Is Implicated in a Novel Class of G-to-A mRNA Editing in WT1 Transcripts

RNA编辑机制

转录后修饰

Classic deamination mRNA changes, including cytidine to uridine (C-to-U) and adenosine to inosine (A-to-I), are important exceptions to the central dogma and lead to significant alterations in gene tr

NIAID Data Ecosystem70

ADAR2 affects mRNA coding sequence edits with only modest effects on gene expression or splicing in vivo

RNA编辑机制

神经递质功能

Adenosine deaminases bind double stranded RNA and convert adenosine to inosine. Editing creates multiple isoforms of neurotransmitter receptors, such as with Gria2 . Adar2 KO mice die of

Taylor & Francis Group2016-03-14 更新50

Full set of E. coli RNA editing assays.

RNA编辑机制

大肠杆菌生物学

Full table of results for all individual E. coli RNA editing assays including standard deviations. C-to-U RNA editing frequencies are given as 100% when no remaining cytidine signal was detectable upo

Figshare2023-08-21 更新40

HEXIM1 Overexpression Alters GATA1 Activity and Promotes Fetal Globin Expression. HEXIM1 Overexpression Alters GATA1 Activity and Promotes Fetal Globin Expression

红细胞生成调控

胎儿血红蛋白表达调控

Erythropoiesis is a highly organized process whereby multipotent HSCs become committed to the erythroid linage and mature into enucleate erythrocytes. Recent work from our lab demonstrated that HEXIM1

NIAID Data Ecosystem60

ATAC-seq reveals GATA-1- and heme-dependent chromatin targeting in erythroid cells.

红细胞生成调控

染色质可及性分析

CRISPR/Cas9-mediated ablation of two Alas2 intronic cis-elements in G1E-ER-GATA1 cells strongly reduced GATA-1-induced Alas2 transcription, heme biosynthesis, and GATA-1 regulation of other vital cons

NIAID Data Ecosystem50

ADAR1-mediated A-to-I RNA editing is essential for erythropoiesis [RNA-seq]

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