Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination
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Drawing on information from SEC-MALLS, DIA-MS, XLMS, negative-stain EM, X-ray crystallography, NMR spectroscopy, secondary structure predictions, and homology models, we applied Bayesian integrative structure determination to investigate the molecular architecture of three NuRD sub-complexes: MTA1-HDAC1-RBBP4 (MHR), MTA1<sup>N</sup>-HDAC1-MBD3<sup>GATAD2CC</sup> (MHM), and MTA1-HDAC1-RBBP4-MBD3-GATAD2A (NuDe). The present dataset pertains to the results of this study.
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2022-11-18



