Dataset related to the article "Evidence of SARS-CoV-2 transcriptional activity in cardiomyocytes of COVID-19 patients without clinical signs of cardiac involvement"

This record contains raw data related to the article "Evidence of SARS-CoV-2 transcriptional activity in cardiomyocytes of COVID-19 patients without clinical signs of cardiac involvement"

Article abstract:

We dissected the characteristics of SARS-CoV-2 cardiac tropism in autopsy heart samples of COVID-19 patients, deceased for respiratory failure without cardiac clinical phenotype. By multiple approaches, we detected viral localization into cardiomyocytes, which did not display cell death hallmarks. In addition, we demonstrated active viral transcription in cardiomyocytes by detecting both sense and antisense SARS-CoV-2 spike RNA. These findings suggest the need of a cardiologic surveillance in survived COVID-19 patients.