Research dataset for Lesion-Specific Design and Oversizing as Strategies for TAVI Optimization: A Patient-Specific Finite Element Study

Data to support the article Lesion-Specific Design and Oversizing as Strategies for TAVI Optimization: A Patient-Specific Finite Element Study.Article abstractTranscatheter aortic valve implantation (TAVI) is a revolutionary intervention for aortic stenosis, yet complications such as paravalvular leakage (PVL) and excessive tissue stress remain prevalent, particularly in anatomies with elliptical aortic roots. This study develops geometric optimization strategies—specifically stent oversizing and lesion-specific design—to enhance sealing performance and reduce adverse mechanical interactions. A patient-specific finite element model of the aortic root was developed from CT imaging, and various stent designs were simulated, including alterations in strut thickness, width, and length. The evaluation compared conventional and modified stent configurations under standardized deployment conditions, including the effect of oversizing. Key metrics such as stress distribution, annulus gap area, and stent–aorta contact were particularly analyzed to assess device performance. A correlation analysis was conducted to identify interdependencies among the structural stiffness of the stents and deployment behaviors. Findings highlight the trade-offs between expansion, sealing, and mechanical response, emphasizing that tailored stent designs—particularly those with localized strut modifications—can achieve improved balance in anatomically challenging cases. The computational framework established in this study supports future TAVI optimization by linking stent design to patient-specific deployment outcomes