Wnt11 binds Fzd7 to regulate convergent extension in Xenopus

Direct binding between XWnt11 and XFzd7 has been demonstrated by co-immunoprecipitation in Xenopus embryos. In this system, Wnt11 and Fzd7 contribute to convergent extension during gastrulation (Djiane et al, 2000).

在非洲爪蟾胚胎中，已通过共免疫沉淀技术证实XWnt11与XFzd7之间的直接结合。在此系统中，Wnt11和Fzd7对原肠形成期间的汇聚延伸过程发挥着重要作用（Djiane等，2000年）。