GWAS summary statistics for major depressive disorder symptoms

Meta-analysed genome-wide association summary statistics for symptoms of major depressive disorder.Clin = Clinical and case-enriched cohorts: Psychiatric Genomics Consortium, , Australian Genetics of Depression Study and Generation Scotland,Comm = Community (not selected for diagnosis) cohorts: ALSPAC, Estonian Biobank, and UK Biobank.Symptoms analysed:MDD1: Depressed mood most of the day, nearly every dayMDD2: Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every dayMDD3: Significant change in weight or appetiteMDD3a: Significant weight loss or decrease in appetiteMDD3b: Significant weight gain or increase in appetiteMDD4: Sleeping too much or not sleeping enoughMDD4a: Insomnia nearly every dayMDD4b: Hypersomnia nearly every dayMDD5: Changes in speed/amount of moving or speakingMDD5a: Psychomotor agitation nearly every dayMDD5b: Psychomotor slowing nearly every dayMDD6: Fatigue or loss of energy nearly every dayMDD7: Feelings of worthlessness or excessive or inappropriate guiltMDD8: Diminished ability to think or concentrate, or indecisivenessMDD9: Recurrent thoughts of death or suicide or a suicide attempt or a specific plan for attempting suicide