Components of the SUMOylation pathway identified as putative AAV host cell restriction factors.
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The screening of the genome-wide siRNA library revealed several factors of the SUMOylation pathway influencing AAV transduction. Protein and gene names are indicated. The screens were carried out in duplicates and each gene was targeted by three different siRNAs. The screen identified 740 putative host cell restriction factors, the table shows the ranking of the factors according to their z-score. Note: in the manuscript the protein identifiers are also used in reference to the corresponding gene.
创建时间：
2015-12-03
